Scientist I, Peptide Purification

AbbVie

  • Madison, WI
  • Permanent
  • Full-time
  • 9 days ago
  • Apply easily
Company DescriptionAbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at . Follow @abbvie on , , , , and .Job DescriptionWe are seeking a highly motivated Peptide Purification Scientist to join our Peptide Synthesis team. The ideal candidate will have hands-on experience in the synthesis and purification of peptides. This individual will investigate, identify, develop, and optimize new methods/techniques to generate reliable and reproducible data in a timely manner. The candidate should also be able to demonstrate broad and versatile technical expertise within discipline.Responsibilities:Laboratory Tasks:
  • Use LC/MS for purification, characterization, and analysis of peptides.
  • Perform routine laboratory techniques: pipetting, reagent reconstitution, calculation of concentrations/dilutions, and accurate weighing of raw materials for instrument setup and compound processing.
  • Setup, maintain, and troubleshoot instruments: HPLC, lyophilizers, peptide synthesizers, centrifuges, rotovap, and balances.
  • Complete hazardous waste training (RCRA/DOT) and manage hazardous waste, including bulking and coordination with handlers.
  • Follow SOPs for standardized activities; recommend improvements as needed.
  • Identify and implement process improvements; conduct optimization experiments when necessary.
  • Troubleshoot and correct process or instrument issues.
Data Analysis & Technical Writing:
  • Maintain accurate lab notebooks and records of all procedures.
  • Analyze and interpret LC/MS data to assess peptide/sample quality.
  • Adjust analytical methods for QC and peptide content.
  • Contribute to development of new data analysis methods.
  • Prepare and review technical reports, SOPs, summaries, and quantitative analyses.
  • Stay current with scientific literature relevant to peptide purification and processes.
Inventory & Training:
  • Manage inventory of reagents and consumables; order supplies as needed.
  • Train new employees in lab techniques and instrument use.
Compliance:
  • Comply with all corporate/divisional policies and procedures.
  • Adhere to standards regarding code of conduct, safety, handling of hazardous materials, GxP compliance, and animal care (if applicable).
Ideal candidates will demonstrate strong problem-solving skills, meticulous attention to detail, and excellent documentation abilities. Experience with RP-HPLC method development and optimization is a plus.Qualifications
  • Bachelor’s Degree or equivalent education with typically 5 years of experience, or Master’s Degree or equivalent education with typically two years of experience.
  • Theoretical and practical knowledge to carry out the job functions.
Additional InformationApplicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​​​​The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.​​We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​​This job is eligible to participate in our short-term incentive programs. ​​​​Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. ​AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.US & Puerto Rico only - to learn more, visitUS & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

AbbVie