Senior Research Scientist; Cell Line Process Development
Curia Global
- Hopkinton, MA
- Permanent
- Full-time
- Generous benefit options (eligible first day of employment)
- Paid training, vacation and holidays (vacation accrual begins on first day of employment)
- Career advancement opportunities
- Education reimbursement
- 401k program
- Pension (for union employees)
- Learning platform
- Serve as a subject matter expert in cell line development to represent functional area for biologics pipeline programs.
- Perform processes including transfection, cloning, characterization, and production optimization to RCB using modern Advanced Instruments and Sartorius equipment.
- Conduct operations of clone screening and identifying of target leaders to develop and optimize stable CHO and HEK293 cell lines suitable for manufacturing.
- Participate in designing and implementing new methods to expand throughput and capacity for CHO cell line process.
- Represent cell line development on multiple projects and effectively communicate results, progress and plans to colleagues and clients
- Interface and collaborate with other functional teams in Discovery, Analytics, QA/QC
- Responsible for technical reports and study records
- Ph.D (2+ years industry experience), MS (5+ years industry experience) or BS. (7+ years industry experience) in Biochemistry, Biophysics, Biology, Chemistry, or Chemical Engineering.
- Track record of accomplishments in the design, development, and implementation of cell culture processes for protein production.
- Experience with VIPSĀ® Seeder, AmbrĀ® 15 bioreactor or equivalents a must.
- Knowledge of bioreactor process and engineering scaling as well as robust understanding of biochemistry and cell metabolic pathways.
- Must be able to clearly and accurately present written data and be comfortable with oral presentations.
- The successful candidate will be responsible for implementing cell line development to support our proprietary cell line technology.
- Candidate must have an in-depth understanding of cell biology and strong hands-on experience of molecular techniques and mammalian culture.
- This role will encompass aspects of upstream process development to support to multiple projects as needed. Candidate will lead upstream process design, optimization, and tech transfer. T
- The candidate will be responsible for executing projects within the laboratory, writing study/research plans, and summarizing data to clients and colleagues via technical reports.
- Candidate must be able to work independently, including planning, trouble shooting and execution of cell line development and new technology assessment.
- Ideal person will initiate implementation of new methods to increase production and capacity for mammalian cell line process development through emerging and novel approaches.