Associate Director, RWE Data Scientist-Gaithersburg, MD

AstraZeneca

  • Gaithersburg, MD
  • Permanent
  • Full-time
  • 2 days ago
Do you have expertise in and a passion for Medical Affairs in Oncology? Would you like to apply your expertise to impact the Associate Director, RWE Data Scientist role at a company that follows the science and turns ideas into life-changing medicines? Then AstraZeneca might be the place for you!At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big, and collaborating to make the impossible a reality. If you are swift to action, confident in your leadership, willing to collaborate, and curious about what science can achieve, then you’re our kind of person.AstraZeneca’s vision in Oncology is to help patients by redefining the cancer treatment paradigm, with the 2030 oncology ambition to have medicines that can potentially treat at least half of all cancers. Our broad pipeline of next-generation medicines is focused principally on five disease areas: breast, lung, liver, ovarian, and hematological cancers. In addition to these tumor types, we are targeting cancers through five key platforms: immunotherapy, the genetic drivers of cancer and resistance, DNA damage repair, HER2, and antibody-drug conjugates, all underpinned by personalized healthcare and biomarker technologies.The RoleThe Centre for Oncology Data Excellence (CODE) is a function that is focused on delivering best in class scientifically rigorous research to support the Global Medical Evidence Generation. Within CODE, Oncology Data & Analytics (ODA) is a key team responsible for RWD analysis, Data Foundation & Governance, Analytics Platforms and Tools and innovative AI capabilities. The study execution within ODA is used for answering key clinical questions, and where applicable, supporting payer or reimbursement submissions.As a member within the ODA team, your collaboration will span across multiple functional stakeholders within Medical Evidence Generation. The ideal candidate for this role will bring a proven track record of delivering value through the utilization of routinely collected data from healthcare settings, providing health analytics and insights in various contexts, including Public Health, Pharmaceutical Research and Development, and Commercial/Payer sectors. They will collaborate with colleagues in Oncology Outcomes Research (O2R), Epidemiology and Statistics to provide scientific and technical guidance on study design, real-world data (RWD) selection, and best practices in RW data utilization. With the rapid development of Generative AI, this role will drive the development and expansion of our GenAI and Agentic AI capabilities.Typical Accountabilities
  • Collaborate with Oncology Outcome Research (O2R) team to maximize the value derived from a variety of real-world data sources, including EMR, claims, registry and primary observational data.
  • Support stakeholders within Medical Affairs in providing access to analytical tools and developing visual analytics to enable self-serving applications for end customers.
  • Maintain a strong insight into the capabilities of in-house RWD to facilitate data source selection for RWE and insights generation.
  • Provide clear technical input, options, and direction to RWD analysis and utilization supporting RWE and insights generation.
  • Help build a capability that becomes a source of sustained competitive advantage for AstraZeneca in identifying, acquiring, integrating, and mining diverse RW data from multiple geographic and healthcare system sources to support evidence generation and real-world studies.
  • Apply ML/AI techniques to analyse complex RWD, including the development of predictive models and algorithms to uncover patterns and insights in healthcare data such as EMR, claims, and observational data
Education, Qualifications, Skills, and ExperienceEssential:
  • PhD or MS in data science, epidemiology, statistics, artificial intelligence, computer science, or related field such as health informatics.
  • Expertise in health data analysis, data visualization, methods development and application using statistical languages such as R, Python, SQL, or SAS.
  • Expertise in advanced visualization platform and visual analytics development, such as Shiny, Tibco Spotfire or Power BI.
  • Experience in real-world evidence and familiarity with health economics, epidemiology, observational study methodologies, and quantitative sciences such as health outcome modelling.
  • Expertise in EMR/Health IT, disease registries, and insurance claims databases.
  • Familiarity in Statistical Analysis Plan (SAP) generation and execution for observational studies.
  • Expertise in integrating Generative AI tools (e.g., GitHub CoPilot) into RWD analysis pipeline to assist in coding, writing, debugging and enhance productivity.
Desirable:
  • Expertise in clinical data standards, medical terminologies, and controlled vocabularies used in healthcare data and ontologies (ICD-9/10, NDC, HCPCS).
  • Demonstrated ability to build long-term relationships with stakeholders, understanding relevant scientific and business challenges at a deep level and translating those into a program of informatics activities that deliver defined value.
  • Ability to lead and manage cross-functional data science projects with track record of peer-reviewed publications and/or regulatory submissions
  • Experience working in a global organization and delivering global solutions.
  • Familiarity with the use of Machine Learning and Artificial Intelligence in the generation of hypotheses within Real-World Data.
  • Experience with AI-empowered software and web application developments in pharmaceutical, biomedical, or healthcare sectors. Hands-on experience with Agentic AI workflow development in common frameworks.
The annual base salary (or hourly rate of compensation) for this position ranges from $135,000-$203,000. However, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles) or to receive a retirement contribution (hourly roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.Date Posted 02-Sep-2025Closing DateOur mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

AstraZeneca