University of Colorado Anschutz Medical CampusDepartment: AnesthesiologyJob Title:Position #00839447 – Requisition #37623Job Summary:The Basak Laboratory in the Department of Anesthesiology is interested in understanding the molecular mechanisms that mediate brain injury and recovery after a cardiac arrest. Our research uses translational animal models of cardiac arrest with cardiopulmonary resuscitation (CPR) to study the role of various molecular pathways in mediating neuronal cell death, synaptic loss, and cognitive dysfunction. Our specific goal is to understand how advanced age affects the brain’s response to an injury induced by a cardiac arrest, with a focus on age-associated inflammation (inflammaging) that is mediated by a protein complex called the inflammasome. We also study how aging-associated changes in microglial cell activity and function alter brain injury after a cardiac arrest, and plan to determine how pharmacologically and genetically targeting microglia and inflammasome function can improve brain function after the injury.We are currently seeking a professional research assistant to support lab management, including the maintenance of the mouse colony, and to assist with ongoing experiments. These experiments include, but are not limited to immunohistochemistry, cognitive behavioral analysis, western blot imaging, RNA quantification, single-cell transcriptomics, and electrophysiology. Key responsibilities will include preparing solutions and samples, operating and maintaining lab instruments, and conducting data collection and analysis. The position offers an excellent opportunity to learn cutting-edge technologies, gain insights into the pathophysiology of brain injury in the setting of ischemia, and support your professional development in a collaborative research environment.The ideal candidate will have a background in neuroscience, cell or molecular biology, or a related field. While experience with techniques such as animal surgery, brain tissue extraction and dissection, fluorescence imaging (epifluorescent, confocal, two-photon, etc.), molecular techniques (such as qPCR, ELISA’s, Western blotting), general histology, animal behavioral analysis, primary neuronal cultures, and fluorescence-activated cell sorting is not required, familiarity with any of these methods will be considered a plus.Key Responsibilities:Monitor animals that have surgeries and provide support for animal husbandry, as needed.Collaborate with and support Principal Investigators (PI) and other stakeholders with laboratory and research functions and provide support researching issues and developing recommendations to resolve process, unit, and related issuesUtilize a variety of laboratory techniques required for research projects; for example, perform experiments and tabulate, analyze research, pick up, transport, and maintain results, samples, documents, materials, and other items as needed.Support analytical testing process using standard lab support knowledge in the collection and review of conditions, including preserving samples, completing sample preparation, documenting, and communicating results also perform pre-analytical, analytical, and post analytical test process and evaluate results produced.Prepare lab for daily operations, including stocking materials, equipment, safety, cleanliness, and related areas as well as disposing of laboratory materials and samples using well established guidelines.Work Location:Onsite – this role is expected to work onsite and is located in Aurora, CO.Why Join Us:The University of Colorado School of Medicine and the Department of Anesthesiology is a world-class medical destination at the forefront of transformative education, science, medicine, and healthcare. The Department of Anesthesiology has several clinical specialties and is a nationally recognized leader in anesthesiology and peri-operative medical education. We are dedicated to developing leaders in anesthesiology and perioperative medicine who demonstrate clinical excellence, professionalism, and a commitment to life-long learning. Our faculty have a resolve to create an exciting academic environment that will build upon what is already recognized as one of the finest residency programs in the country, and by advancing education within our specialty, we continue to improve the lives of learners and patients in a complex and evolving world of medicine.Why work for the University?We have AMAZING benefits and offer exceptional amounts of holiday, vacation and sick leave! The University of Colorado offers an excellent benefits package including:Medical: Multiple plan optionsDental: Multiple plan optionsAdditional Insurance: Disability, Life, VisionRetirement 401(a) Plan: Employer contributes 10% of your gross payPaid Time Off: Accruals over the yearVacation Days: 22/year (maximum accrual 352 hours)Sick Days: 15/year (unlimited maximum accrual)Holiday Days: 10/yearTuition Benefit: Employees have access to this benefit on all CU campusesECO Pass: Reduced rate RTD Bus and light rail serviceThere are many additional perks & programs with the .Qualifications:Minimum Qualifications (Entry Professional)Bachelor’s degree in biology, molecular biology, neuroscience, chemistry, genetics or related fieldMinimum Qualifications (Intermediate Professional)Bachelor’s degree in biology, molecular biology, chemistry, genetics or related fieldOne (1) year professional level research experience performing animal-related work in an experimental or wet labA combination of education and related technical/paraprofessional experience may be substituted for the bachelor’s degree on a year for year basisApplicants must meet minimum qualifications at the time of hire.Preferred Qualifications (Entry Professional)Master’s degree in biology, neuroscience, molecular biology, chemistry, genetics or related fieldPrior experience or background within an experimental or wet labPrior experience with animal surgeriesPrior experience performing confocal or two-photon imagingPrior experience with immunohistological techniquesPreferred Qualifications (Intermediate Professional)Master’s degree in biology, molecular biology, chemistry, genetics or related fieldTwo (2) years of experience in an experimental or wet laboratory performing animal surgeries or confocal or two-photon imaging.Prior experience with immunohistological techniquesKnowledge, Skills and Abilities:Proficient knowledge of basic laboratory techniques including safety procedures and techniquesAbility to communicate effectively, both in writing and orallyAbility to establish and maintain effective working relationships with employees at all levels throughout the institutionOutstanding customer service skillsKnowledge of basic human anatomy, physiology medical terminologyAbility to interpret and master complex research protocol informationHow to Apply:For full consideration, please submit the following document(s):1. A letter of interest describing relevant job experiences as they relate to listed job qualifications and interest in the position2. Curriculum vitae / Resume3. Three to five professional references, including name, address, phone number (mobile number if appropriate), and email addressQuestions should be directed to: Abigail Jacoba, for position or application questions. Dr. Jacob Basak, for work related questions.Screening of Applications Begins:Immediately and continues until position is filled. For best consideration, apply by 09/04/2025.Anticipated Pay Range:The starting salary range for this position has been established as:Entry Professional: $46,274 - $58,861Intermediate Professional: $50,357 - $64,054The above salary range (or hiring range) represents the University’s good faith and reasonable estimate of the range of possible compensation at the time of posting. This position may be eligible for overtime compensation, depending on the level.Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.Total Compensation Calculator:ADA Statement:Equal Employment Opportunity Statement:The University will provide reasonable accommodations to applicants with disabilities throughout the employment application process. To request an accommodation pursuant to the Americans with Disabilities Act, please contact the Human Resources ADA Coordinator at .CU is an Equal Opportunity Employer and complies with all applicable federal, state, and local laws governing nondiscrimination in employment. We are committed to creating a workplace where all individuals are treated with respect and dignity, and we encourage individuals from all backgrounds to apply, including protected veterans and individuals with disabilities.Background Check Statement:The University of Colorado Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background investigations for all prospective employees.Vaccination Statement:CU Anschutz strongly encourages vaccination against the COVID-19 virus and other . If you work, visit, or volunteer in healthcare facilities or clinics operated by our affiliated hospital or clinical partners or by CU Anschutz, you will be required to comply with the vaccination and medical surveillance policies of the facilities or clinics where you work, visit, or volunteer, respectively. In addition, if you work in certain research areas or perform certain safety sensitive job duties, you must enroll in the .
