Career Category Medical AffairsJob DescriptionJOIN AMGEN’S MISSION OF SERVING PATIENTSAt Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year.As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.Executive Medical Director, US Medical Affairs LeadLiveWhat you will doLet’s do this. Let’s change the world. In this vital role as Executive Medical Director, US Medical Affairs Lead, you will be accountable for the development and execution of the US medical affairs strategy for the Thyroid Eye Disease franchise (teprotumumab-trbw/TEPEZZA) and pipeline with the objective of maximizing Amgen’s value proposition.TEPEZZA® (teprotumumab-trbw) is the first and only FDA-approved therapy for Thyroid Eye Disease (TED), a serious, progressive, and potentially vision-threatening autoimmune condition. TEPEZZA is a fully human monoclonal antibody that targets and inhibits the insulin-like growth factor-1 receptor (IGF-1R), a key driver of TED pathophysiology. By blocking IGF-1R signaling, TEPEZZA has been shown to reduce inflammation, orbital tissue expansion, and proptosis, improving both functional and quality-of-life outcomes.Clinical studies have demonstrated its efficacy and safety across patients with active and chronic low–clinical activity score (CAS) TED, highlighting its broad impact on disease management. TEPEZZA represents a transformative advancement for patients, with ongoing research exploring its potential in other IGF-1R–mediated conditions.At Amgen, we are deeply committed to advancing innovative therapies for rare diseases, where the need is greatest and the impact can be life changing. The development and success of TEPEZZA exemplify this mission, underscoring our dedication to bringing breakthrough treatments to patients who have long been underservedResponsibilities:Developing the US medical strategy for teprotumumab through deep understanding of medical practice to maximize access and reimbursementContributing to the product strategy for teprotumumab and TED franchise pipelineDeveloping and leading external stakeholder plan, management, communication, evidence generation, and medical educationDeveloping and leading execution of a US medical communication strategy, including clinical narrative framework, scientific platform, core content, congresses, and publicationsEngaging US external stakeholders to strengthen the understanding of the unmet need and medical value of Teprotumumab and TED franchise pipelineElevating Amgen’s reputation as a science-based and patient focused reliable partnerPartnering on evidence generation and ensuring key regional/local needs are addressedProviding medical insights and advice internallyWinWhat we expect of youWe are all different, yet we all use our unique contributions to serve patients. The candidate we seek is an experienced leader with the following qualifications.Basic Qualifications:Doctorate degree & 6 years of directly related experience ORMaster’s degree & 10 years of directly related experience ORBachelor’s degree & 12 years of directly related experience AND6 years of managerial experience directly managing people and/or leadership experience leading teams, projects, programs or directing the allocation of resourcesPreferred Qualifications:MD, PharmD or PhD degree from an accredited school3 years of Medical Affairs experience in Immunology, ophthalmology or pharmacologyRare disease knowledge and experience5 or more years of Medical Affairs experience in the biopharmaceutical industry (biotech, pharmaceutical or CRO) that includes collaborations with integrated delivery networks, accountable care organizations, and/or payers5 or more years of Rare Disease experience3 or more years of clinical research experience and/or basic science combined with clinical teaching and patient care activitiesFamiliarity with US regulatory organizations, guidelines, and practicesKnowledge of Good Clinical Practices (GCP) and US regulations and guidelinesHistory of solving problems while exhibiting superior judgment and a balanced, realistic understanding of issuesKnowledge of pharmaceutical product development, product lifecycle, and commercialization processes, including but not limited to, clinical operations, commercial, regulatory, and medical affairsThey will also embody the Amgen leadership attributes which are:Inspire: Create a connected, inclusive, and inspiring work environment that empowers talent to thriveAccelerate: Enable speed that matches the urgency of patient needs by encouraging progress over perfectionIntegrate: Connect the dots to amplify the collective power of Amgen to drive results for patients, staff, and shareholdersAdapt: Lead through change by adapting to an ever-changing environment and defining a clear course of action to deliver resultsThriveWhat you can expect of usAs we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.The annual base salary range for this opportunity in the U.S. is $343,334 - $403,728.In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.A discretionary annual bonus program, or for field sales representatives, a sales-based incentive planStock-based long-term incentivesAward-winning time-off plans and bi-annual company-wide shutdownsFlexible work models, including remote work arrangements, where possibleAs an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position..Salary Range 343,334.00 USD - 403,728.00 USD
