Scientist (Seattle, WA)Regeneron Pharmaceuticals, Inc. seeks a Scientist (Seattle, WA) to assist with researching literature and market landscape to identify potential therapeutic targets and associated product concepts. Devise experimental plans to validate identified targets. Generate libraries of immunotherapeutic proteins and perform assay-based screening to identify promising hits. Perform standard T cell characterization assays, including cocultures to evaluate antigen specificity, target cell cytotoxicity, and T cell proliferation. Analyze high-throughput data using bioinformatics workflows in R and adjust parameters as necessary. Employ state-of-the-art automation instruments and collaborate with automation scientists to refine protocols. Provide guidance and mentorship to junior interns. Interpret, and present data at working groups to help the broader department make datadriven decisions. 4% domestic travel required.SALARY RANGE: $79,100.00 – $129,100.00 per yearJob Requirements:Requires a Bachelor’s degree in Cell and Molecular Biology, Immunology, Biochemistry, Biology or related field and 3 years of pharmaceutical/biotech industry research experience. Employer will also accept a Master’s degree in the mentioned fields and 1 year of specified experience. Must have experience with: Cell signaling pathways, protein engineering and cancer immunotherapies; Molecular biology techniques such as DNA construct design and cloning, including large-scale library cloning and quality assessment using Next-Generation Sequencing; Mammalian cell culture and cell line engineering by CRISPR-Cas9 genome editing; Common laboratory automation platforms, such as Hamilton and Integra Assist Plus; Multicolor analytical flow cytometry, as well as fluorescence activated cell sorting (FACS); Common data analysis software including FlowJo and Graphpad Prism; Bioinformatic analysis of sequence data using R and/or Python; Driving results in multiple projects simultaneously and planning and organizing work activities to meet schedules and deadlines; and Interpreting results and presenting them effectively in a variety of team settings and contributing constructively to scientific discussions. Must have scientific publications in the pharmaceutical/biotech industry research field. 4% domestic travel required.We have an inclusive & diverse culture that provides comprehensive benefits, which often incl (depending on location) health/wellness programs, fitness centers, equity awards, annual bonuses, & PTO for eligible employees at all levels. See for details.To apply for this position, please visit Reference code: R40083.Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits, which often include (depending on location) health and wellness programs, fitness centers, equity awards, annual bonuses, and paid time off for eligible employees at all levels!Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business.For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions. For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location.Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc.
