Director, Head of Antibody Discovery
abpro
- Woburn, MA
- Permanent
- Full-time
- Lead Abpro’s antibody discovery R&D from target to IND (investigational new drug), with a focus on immune-oncology and infectious diseases.
- Execute on all aspects of antibody generation and characterization using hybridoma, single B cell cloning and display technology platforms. including target selection, hit generation and optimization, protein expression/purification, and antibody engineering.
- Provide leadership to a team of experienced scientists and lab personnel of all experience.
- Provide and maintain state-of-the-art expertise and technical capabilities in the field of biologics discovery and identify opportunities for scientific novelty and innovation.
- Provide leadership and manage discovery programs both internally and through partnership.
- Manage external partnership research and CRO activities.
- Contribute to patent filing and scientific publications for the company.
- Ph.D. in Biochemistry, Molecular Biology, Immunology, or related field
- Minimum 10-15 years of experience in biologics drug discovery and pre-clinical development, of which at least 5 years in a leadership role
- Thorough understanding of the biologics drug discovery process from target validation and therapeutic concept through the transition to clinical development
- In-depth knowledge and technical expertise of a broad spectrum of therapeutic modalities in biologics, including mono- and multi-specific antibodies and other biologics
- Extensive experience with cutting-edge antibody discovery technologies, including hybridoma, single B cell cloning, and display platform
- Strong communication skills, written and oral
- Self-motivated and collaborative, with excellent time management skills
- Ability to work on multiple projects in a fast-paced excellence-driven environment