
Senior Research Scientist, TB Modeling
Bill & Melinda Gates Foundation
- Seattle, WA
- Permanent
- Full-time
Within IDM, the goals of the Product Discovery and Development (PDD) team are to advance disease control by integrating data and developing novel tools across pathogens to enable more targeted, efficient, and equitable public health decision-making. We develop and apply rigorous modeling to understand and capture the drivers of heterogeneous disease risk and intervention impact. PDD aims to improve understanding of how products and interventions will perform in heterogeneous populations and to generate evidence on synergies across pathogens and within individuals and populations.Application Deadline: September 19, 2025Your RoleWe seek a Senior Research Scientist to join the PDD team to lead efforts in dynamic modeling of tuberculosis (TB) to support the design, evaluation, and strategic deployment of TB prevention and treatment products. This candidate will be central to advancing our scientific understanding of TB epidemiology and refining and applying TB transmission models that capture the nuanced heterogeneity in disease risk, natural history, and intervention impact to inform product development and public health impact strategies. The candidate will adapt knowledge, ideas, and research methodology from different disciplines to develop innovative approaches to longstanding challenges in the field of global health and clearly communicate sophisticated research methods to diverse audiences.What You’ll Do
- Design, calibrate, and refine a novel dynamic transmission model of TB that is anchored in observable states, captures physiologically important features of tuberculosis and setting-specific covariation and is optimized for product evaluation and surveillance design.
- Incorporate new insights from TB biology, epidemiology, and clinical research into mechanistic modeling frameworks.
- Identify and integrate key drivers of heterogeneity in TB risk and disease progression, including demographic, social, and biological factors.
- Develop scenarios to forecast product performance across varied settings and populations.
- Lead or co-author high-impact research publications, reports, and presentations relevant to TB modeling and product strategy.
- Partner with internal teams and external collaborators (e.g., academic groups, global health organizations, product developers) to align modeling work with real-world data and R&D pipelines.
- Engage with global health stakeholders to communicate model findings and inform policy, product positioning, and implementation strategies.
- PhD in epidemiology, biostatistics, computational biology, mathematical modeling, or a related field.
- 5+ years of experience in infectious disease modeling, with a strong preference for candidates with TB modeling expertise.
- Proven track record of publishing in peer-reviewed scientific journals and presenting research at conferences.
- Strong programming skills in Python and R.
- Ability to translate complex scientific results into actionable insights for non-technical audiences.
- Eagerness to learn to communicate diverse and technical work to partners
- Demonstrated ability to work productively independently and as part of a team
- Attention to detail and high standard for quality of work product.
- Experience working on collaborative projects, with significant software components.
- Ability to initiate, organize, and manage research projects and clearly communicate analysis results to diverse audiences
- Must be highly inquisitive, self-motivated and results oriented