Senior Scientist, Oligonucleotide Chemistry Development

Danaher

  • Bothell, WA
  • $98,000-135,000 per year
  • Permanent
  • Full-time
  • 15 days ago
Bring more to life.Are you ready to accelerate your potential and make a real difference within life sciences, diagnostics and biotechnology?At Cepheid, one of 15+ operating companies, our work saves lives—and we’re all united by a shared commitment to innovate for tangible impact.You’ll thrive in a culture of belonging where you and your unique viewpoint matter. And by harnessing Danaher’s system of continuous improvement, you help turn ideas into impact – innovating at the speed of life.At Cepheid, we are passionate about improving health care through fast, accurate, molecular diagnostic systems and tests. As a member of our team, you’ll get to make an immediate, measurable impact on a global scale, within an environment that fosters career growth and development. Our mission drives us to develop groundbreaking solutions for the world’s most complex health challenges. Together, we bring MORE change to the world.Learn about the which makes everything possible.The Senior Scientist, Oligonucleotide Chemistry Development, is responsible for optimization of automated synthesis and purification of oligonucleotides for PCR applications.This position reports to the Director, Oligo Development and is part of the Chemistry R&D Department located in Bothell, Washington and will be an on-site role.In this role, you will have the opportunity to:
  • Serve internal customers with R&D grade oligonucleotides: accept orders, plan, synthesize, purify, analyze, formulate and ship
  • Develop and improve processes for efficient solid phase synthesis, deprotection and purification of oligonucleotides, conduct verification experiments and draft SOPs
  • Evaluate new analysis methods and equipment aligned with the current oligonucleotide processing protocols and/or methods that could be easily adopted/transferred to manufacturing
  • Prepare reports, and draft slide decks and make presentations for periodic reviews, technical meetings and publications
  • Review and approve reports, protocols, etc. using product life cycle management software and/or electronic document management systems (e.g. Agile, Documentum, etc.)
The essential requirements of the job include:
  • Bachelor’s degree in Synthetic Chemistry with 5+ years of experience in solid phase synthesis OR Master’s degree in Synthetic Chemistry with 3+ years OR Doctoral degree in Synthetic Chemistry with 1+ years of work experience in solid phase synthesis
  • Fundamental knowledge of organic chemistry and analytical chemistry techniques, proficiency with analytical instruments: HPLC, UHPLC, LC-MS, UV-Vis
  • Synthesis, purification, characterization, and formulation of oligonucleotides, maintenance and troubleshooting laboratory equipment
  • Conducting laboratory work and preparing process documentation
  • Sound knowledge of laboratory safety and biosafety practices, adherence to all chemical and lab safety regulations
Travel, Motor Vehicle Record & Physical/Environment Requirements:
  • This role may involve occasional exposure to chemical odors, all of which are well within established safety and occupational exposure limits. Appropriate PPE and ventilation are provided in accordance with safety protocols.
It would be a plus if you also possess previous experience in:
  • Operation of automated solid phase DNA/RNA synthesizer (MerMade, AKTA, etc.)
  • Work in cGMP environment with proven documentation competency
Cepheid, a Danaher operating company, offers a broad array of comprehensive, competitive benefit programs that add value to our lives. Whether it’s a health care program or paid time off, our programs contribute to life beyond the job. Check out our benefits at .The annual salary range for this role is $98,000 to $135,000 USD. This is the range that we in good faith believe is the range of possible compensation for this role at the time of this posting. This range may be modified in the future.This job is also eligible for bonus/incentive pay.We offer a comprehensive package of benefits including paid time off, medical/dental/vision insurance and 401(k) to eligible employees.Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole discretion unless and until paid and may be modified at the Company’s sole discretion, consistent with the law.Join our winning team today. Together, we’ll accelerate the real-life impact of tomorrow’s science and technology. We partner with customers across the globe to help them solve their most complex challenges, architecting solutions that bring the power of science to life.For more information, visit .Danaher Corporation and all Danaher Companies are committed to equal opportunity regardless of race, color, national origin, religion, sex, age, marital status, disability, veteran status, sexual orientation, gender identity, or other characteristics protected by law.The U.S. EEO posters are available .We comply with federal and state disability laws and make reasonable accommodations for applicants and employees with disabilities. If reasonable accommodation is needed to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please contact:1-202-419-7762 or .

Danaher