We invite applications for a postdoctoral position in the eBERlight group within the X-ray Science Division at Argonne National Laboratory. The selected candidate will lead the expansion of the protein expression platforms, currently utilizing E. coli and mammalian cell lines, to onboard other microbial systems (e.g., fungi), insect-cell (baculovirus) systems, plant-based expression (in planta), and cell free methods.Key Responsibilities:Development and optimization of vector constructs and expression condition characterization of protein yields and quality, and large-scale protein production for structural biology and other applications (ligand binding, enzymatic activity etc.).Involvement in the research pertinent to specific protein targets will be expected as well, along with presentation of findings to the community through publications and presentations.Position RequirementsPh.D. in Molecular Biology, Biochemistry, Biotechnology, Plant Biology, Protein Engineering, Microbiology, or a related field completed in the past five years or soon-to-be completed.Demonstrated experience in at least two of the following:Fungal protein expressionInsect-cell (baculovirus) expression platforms.Plant-based (in planta) expression systems.Membrane proteins production and purificationStrong molecular biology skills (cloning, vector design, transformation), protein purification and analysis, and quantitative data analysis.Excellent communication and teamwork capabilities, with a track record (or potential) in writing publications and presenting scientific results.Interpersonal skills, oral and written communication skills, and ability to interact with people at all levels both within and outside the laboratory.Ability to model Argonne’s core values of impact, safety, respect, integrity, and teamwork.Preferred Knowledge, Skills, and ExperiencePrior experience with high-throughput or computational protein design/screening techniques.Background in structural biology (CryoEM/crystallography)Knowledge of in planta systems—stable or transient expression, agroinfiltration techniques, or engineering of plant chassis.Job Family PostdoctoralJob Profile Postdoctoral AppointeeWorker Type Long-Term (Fixed Term)Time Type Full timeThe expected hiring range for this position is $70,758.00-$117,925.00.Please note that the pay range information is a general guideline only. The pay offered to a selected candidate will be determined based on factors such as, but not limited to, the scope and responsibilities of the position, the qualifications of the selected candidate, business considerations, internal equity, and external market pay for comparable jobs. Additionally, comprehensive benefits are part of the total rewards package.Click to view Argonne employee benefits!As an equal employment opportunity employer, and in accordance with our core values of impact, safety, respect, integrity and teamwork, Argonne National Laboratory is committed to a safe and welcoming workplace that fosters collaborative scientific discovery and innovation. Argonne encourages everyone to apply for employment. Argonne is committed to nondiscrimination and considers all qualified applicants for employment without regard to any characteristic protected by law.Argonne employees, and certain guest researchers and contractors, are subject to particular restrictions related to participation in Foreign Government Sponsored or Affiliated Activities, as defined and detailed in United States Department of Energy Order 486.1A. You will be asked to disclose any such participation in the application phase for review by Argonne's Legal Department.All Argonne offers of employment are contingent upon a background check that includes an assessment of criminal conviction history conducted on an individualized and case-by-case basis. Please be advised that Argonne positions require upon hire (or may require in the future) for the individual be to obtain a government access authorization that involves additional background check requirements. Failure to obtain or maintain such government access authorization could result in the withdrawal of a job offer or future termination of employment.
