LAB RESEARCH ANALYST I

Duke University

  • Durham, NC
  • $51,448-77,945 per year
  • Permanent
  • Full-time
  • 1 day ago
School of MedicineEstablished in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations.Be You.The Global Health Discovery Collaboratory (GHDC) Antibody Dynamics team at the Duke University Center for Human Systems Immunology ( ) is seeking a detail-oriented scientist to fulfill a key role as Lab Research Analyst I. The incumbent of this position in the Biophysical Immunology team will perform assays to assess the kinetics of antibody-antigen interactions in therapeutic antibody development and in responses to vaccination against global health pathogens including those that cause malaria and tuberculosis. The study results generated by the person in this role will inform human clinical and pre-clinical trials for vaccines, accelerate antibodies and other biologics candidates to clinic. The person in this role will also play a key role in assay development and standardization and in testing feasibility of novel methods.Minimum Requirements:
  • Work requires a bachelor's degree in botany, biology, zoology, psychology or other directly related scientific field.
  • Work requires two years of research experience. A related master's degree may offset required years of experience on a 1:1 basis, e.g., a two year master's degree in lieu of two years of experience. OR AN EQUIVALENT COMBINATION OF RELEVANT EDUCATION AND/OR EXPERIENCE
Preferred Qualifications:
  • Bachelor's degree in chemistry, Biochemistry, Biophysics, Bioengineering, Biotechnology, biological science or related field,
  • Strong background in laboratory techniques with technical precision
  • Two years of research experience performing SPR/BLIassays or equivalent combination of relevant education and research experience
  • Must be able to manage multiple and rapidly changing priorities and have the ability to quickly learn new skills
  • Must be detail-oriented and well organized with strong communication skills and the ability to work in a fast-paced interactive team environment.
  • Experience in using Mathematica and R-studio packages and working in GMP/GCLP compliant laboratories will be a plus.
Other Requirements:This position is onsite. The work is performed on-site or at a designated assignment location.Be Bold.
  • Design and perform high throughput surface plasmon resonance (SPR) and bio-layer interferometry (BLI) assays to identify lead monoclonal antibody and other biologics candidates for therapeutics development.
  • Perform complex and highly technical BLI and SPR assays in the laboratory to evaluate antibody dynamics in samples from clinical and preclinical vaccine trials. Carefully and accurately document assay conditions, results, and quality control findings and report them promptly to meet deadlines.
  • Play a key role in the development and standardization of new assays, participating in discussions of next steps for follow up assays and in assay design.
  • Perform bio-layer interferometry (BLI), surface plasmon resonance (SPR), and other assays in the lab to develop new methods and protocols, optimize reagents, test various conditions, and determine feasibility of assays using novel antigens.
  • Assist the laboratory and project managers by contributing to the overall effort to streamline the workload, improve the efficiency of the Antibody Dynamics team, and contribute to the daily laboratory effort to adhere to Good Clinical Laboratory Practice (GCLP) guidelines. Assist with writing and editing Standard Operating Procedures (SOP's).
  • Maintain laboratory and associated equipment in a clean, well-ordered, and functional manner. Keep supplies on hand with a well-planned inventory and ordering system. Maintain laboratory notebook in an orderly fashion for tracking experiments and results. Provide written updates of work each week.
Choose Duke.Join our award-winning team and be part of an inclusive culture that is committed to providing outstanding patient care, training tomorrow's leaders, and conducting innovative research. You'll also benefit from Duke's competitive benefits package, including health insurance plans, generous paid time off, retirement programs with employer contributions, tuition assistance for employees and their children, and more.Screening of Applications: Screening continues until the position is filled.Anticipated Pay Range:Duke University provides an annual base salary range for this position as USD $51,448 to USD $77,945. Duke University considers factors such as (but not limited to) scope and responsibilities of the position; candidate 's work experience, education/training, and key skills; internal peer equity; as well as market and organizational considerations when extending an offer.Your total compensation goes beyond the dollars on your paycheck. Duke provides comprehensive and competitive medical and dental care programs, generous retirement benefits, and a wide array of family-friendly and cultural programs to eligible team members. Learn more at https://hr.duke.edu/benefits/Minimum QualificationsDuke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age,color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation,or veteran status.Duke aspires to create a community built on collaboration,innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas-an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members ofour community have a responsibility to uphold these values.Anticipated Pay Range:Duke University provides an annual base salary range for this position as USD $ 51,448.00 to USD $77,945.00. Duke University considers factors such as (but not limited to) scope and responsibilities of the position; candidate' s work experience, education/training, and keyskills; internal peer equity; as well as market and organizational considerations when extending an offer.Your total compensation goes beyond the dollars on your paycheck. Duke provides comprehensive and competitive medical and dental care programs, generous retirement benefits, and a wide array of family-friendly and cultural programs to eligible team members. Learn more at:https://hr.duke.edu/benefits/Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/ or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.EducationWork requires a bachelor's degree in botany, biology, zoology, psychology or other directly related scientific field.ExperienceWork requires two years of research experience. A related master'sdegree may offset required yearrs of experience on a 1:1 basis, e.g., a two year master's degree in lieu of two years of experience. OR AN EQUIVALENT COMBINATION OF RELEVANT EDUCATION AND/OR EXPERIENCE.Duke is an Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex (including pregnancy and pregnancy related conditions), sexual orientation or military status.Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends onthe robust exchange of ideas-an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.

Duke University