Associate Director, Biostatistics
Alexion Pharmaceuticals
- Boston, MA
- Permanent
- Full-time
- For a project or indication in clinical or preclinical therapeutic areas
- Leading the delivery and oversight on a multiple studies/indication within a project, potentially as a Global Project Statistician for a standard drug project
- Contributing to statistical methodological advances
- Lead the statistical thinking and contributions to the delivery of studies, development plans, regulatory strategy, health technology assessment and/or commercial activities
- Direct project work, including statistical staff and/or CRO partners, to ensure delivery to standards, quality, and time
- Develop design options and provide high quality decision support to enable the business to make informed decisions about a study or project
- Quantify the benefit, risk, value, and uncertainty of the emerging asset/product profile
- Investigate and apply novel statistical approaches, for relevant statistical issues and/or regulatory guidance and/or value demonstration, including modelling and simulation
- Leverage standardization to maximize global data integration and interpretability
- Mentor/coach and support the education and training of statistics staff
- MSc/PhD in Statistics, Mathematics (containing a substantial statistical component), or recognized equivalent to stats MSc
- Strong knowledge of programming in R and/or SAS
- Knowledge of the technical and regulatory requirements related to the role
- Excellent communication skills, and ability to build strong relationships
- Flexible, well-organized, and possess the ability to work well under pressure
- The duties of this role are generally conducted in an office environment. As is typical of an office-based role, employees must be able, with or without an accommodation to: use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving and non-linear thought, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours.
- PhD in Statistics/Biostatistics is preferred.
- Project management skills
- Proficiency in SAS and R languages
- Knowledge of Bayesian statistics from theory to computation is a plus.